Education
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Ph D, Chemical Engineering
— UC Berkeley (1984) Foam Spray Drying of Foods
Publications
- Development of a novel analytical sensor utilizing Ni-NTA and His-tag affinity for at-line measurement of binding proteins 2024
- Purification challenges for the portable, on-demand, point-of-care production of biologics 2022
- Metal-semiconductor sorting of large-diameter single-wall carbon nanotubes by pH-dependent binding to a hydrophobic-interaction adsorbent 2021
- Manufacturing Biological Medicines on Demand: Safety and Efficacy of GCSF in a Mouse Model of Total Body Irradiation 2020
- Evaluation of chromatofocusing as a capture method for monoclonal antibody products 2018
- Cell-Free Biomanufacturing 2018
- Improving the recombinant human erythropoietin glycoslyation using microsome supplementation in CHO cell-free system 2018
- Cell free expression of a therapeutic protein: expression, purification, and characterization of recombinant streptokinase using a CHO lysate 2018
- Displacement chromatography of proteins using a retained pH front in a hydrophobic charge induction chromatography column 2015
- Chromatofocusing 2015
- Development of Chromatofocusing Techniques Employing Mixed Mode Column Packings for Protein Separations 2014
- High Performance Liquid Chromatography in the Undergraduate Chemical Engineering laboratory 2013
- Monoclonal Antibody Heterogeneity Analysis and Deamidation Monitoring using High-Performance Cation-Exchange Chromatofocusing using Simple, Two Component Buffer Systems 2013
Creative Publications
- Metal-semiconductor sorting of large-diameter single-wall carbon nanotubes by pH-dependent binding to a hydrophobic-interaction adsorbent 2021
Presentations
- Application of Mechanistic Modeling for the Understanding of Tailing in High Performance Liquid Chromatography (HPLC). 2024
- Development of a novel analytical sensor utilizing Ni-NTA and His-tag affinity for at-line measurement of binding proteins. 2024
- Application of mechanistic modeling for the understanding of tailing in HPLC 2023
- Applications of scientific machine learning to the modeling of chromatography 2022
- Chromatographic sorting of carbon nanotubes 2019
- Design of protein purification methods for on-demand biologics 2019
- Monoclonal Antibody Capture Methods Using Chromatofocusing 2018
- Experimental and theoretical studies of protein adsorption onto ion exchange and mixed mode chromatographic column packings 2018
- Development and validation of a purification platform for proteins expressed in a CHO cell-free system 2018
- Evaluation of chromatofocusing and related ion exchange methods as alternatives to protein A chromatography in the purification of antibodies 2018
- Investigation of charge-based chromatographic methods for sorting nanotube chiral forms 2018
- Development and assessment of chromatofocusing and related alternatives to protein A chromatography for the purification of antibodies 2018
- Prediction and correlation of protein adsorption in ion exchange and mixed mode chromatography 2018
- Evaluation of chromatofocusing and related ion exchange methods as alternatives to protien A chromatography in the purification of therapeutic proteins 2017
- Development and validation of an IMAC purification platform for His-tagged proteins expressed in a CHO cell-free system 2017
- Fundamental studies of the mechanism of ion exchange chromatography 2017
- Process development tools for the purification of therapeutic antibody products using non-affinity capture methods 2017
- New methods for the chromatography of peptides and proteins 2014
- Novel chromatofocusing methods for elution of IgG from Protein A affinity columns 2014
- Hybrid methods for the chromatofocusing of proteins 2013
Grants and Contracts
- ATIP: Novel methods for determination of Hb A1c 2024
- CASTing Biologics on Demand 2013
- Scalable Separation of Single Walled Carbon Nanotubes 2013
- Novel mixed-mode chromatographic processes
- NSF Supplement: Scalable Separation of Single Walled Carbon Nanotubes
Patents and Intellectual Property
- System and method for production of on-demand proteins in a portable unit for POC delivery 2025
- System and method for production of on-demand proteins in a portable unit for POC delivery 2024
- Factory on a chip for production of biologically derived medicine/biopharmaceuticals/biologics/biotherapeutics 2024
Courses Taught
- Separation Processes
- Doctoral Diss Research
- Transport I:Fluids
- Transport I:Fluids
- Doctoral Diss Research
- Transport Phenomena
- Separation Processes
- Doctoral dissertation research
- MS thesis research
- Independent Research
- Transport Phenomena