Govind Rao

Govind Rao

Department of Chemical, Biochemical and Environmental Engineering

College of Engineering and Information Technology

Center for Advanced Sensor Technology

Education

Publications

  • Wearable Transdermal Biosensors 2024 Wearable Biosensing in Medicine and Healthcare · Springer, Singapore · pp. 89–109 Govind Rao, Venkatesh Srinivasan, Zach Sheffield, Preety Ahuja, Sanjeev Kumar, Xudong Ge
  • Development of a novel analytical sensor utilizing Ni-NTA and His-tag affinity for at-line measurement of binding proteins 2024 IFPAC Annual Meeting 2024 Revati Kadolkar, Vikash Kumar, Venkatesh Srinivasan, Sanjeev Kumar, Douglas D Frey, Govind Rao
  • Affordable Hand-held Portable Spectroscopy Technology for PAT applications 2024 IFPAC Annual Meeting 2024 Tithi Prajapati, Mike Tolosa, Venkatesh Srinivasan, Govind Rao
  • A Biosustainable Microfluidic Electrochemical Sensor for Real-time Monitoring of Nitrate in Groundwater and Streams 2023 MWMC Annual Conference 2023 Agenda Revati Kadolkar, Sai Kiran Mani, Tithi Prajapati, Preety Ahuja, Mike Tolosa, Venkatesh Srinivasan, Sanjeev Kumar, Mary McWilliams, Claire Welty, Govind Rao
  • Wood microfluidic engineering: Development of highly stable polymer nanocomposite electrochemical nitrate sensor 2023 U.S. Provisional Patent Application No. 63/520,532 filed on August 18, 2023 · Submitted Govind Rao, Sanjeev Kumar, Venkatesh Srinivasan, Preety Ahuja
  • An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithson using cell free system to mitigate pandemics 2023 New Biotechnology · 76 · pp. 13-22 Douglas D Frey, Govind Rao, Shayan Borhani, Aaron Thole, Max Levine, Barry O'Keef, James Swartz
  • Air-permeable redox mediated transcutaneous CO2 sensor 2023 Chemical Engineering Journal · 457 · pp. 141260 Preety Ahuja, Sanjeev Kumar, Govind Rao, Xudong Ge
  • Air-permeable redox mediated transcutaneous CO2 sensor 2023 Chemical Engineering Journal · 457 · pp. 141260 Preety Ahuja, Sanjeev Kumar, Govind Rao, Xudong Ge
  • Purification challenges for the portable, on-demand, point-of-care production of biologics 2022 no · Current Opinion in ChE · 36 · pp. 10082 Aaron Thole, Douglas D Frey, Govind Rao
  • Rapid and Low-Cost Sampling for Detection of Airborne SARS-CoV-2 in Dehumidifier Condensate 2021 Biotechnol. Bioeng. · 118 · pp. 3029-3036 P. Moitra, M. Alafeef, K. Dighe, P. Ray, Douglas D Frey, Dipanjan Pan, Govind Rao
  • Manufacturing Biological Medicines on Demand: Safety and Efficacy of GCSF in a Mouse Model of Total Body Irradiation 2020 Biotechnol. Prog. · 36 (3) · pp. e2970 Rajani Adija, Abhay Andar, David Bergenson, Sevda Deldari, Douglas D Frey, Xudong Ge, Yang Liu, Govind Rao, Lynn Wong
  • Low Cost Customizable Microscale Toolkit for Rapid Screening and Purification of Therapeutic Proteins 2019 Biotechnol. Bioeng. · 116 · pp. 870-881 Douglas D Frey, Douglas Frey, Douglas Frey, Govind Rao, Iordan V Kostov, Douglas Frey
  • Improving the recombinant human erythropoietin glycoslyation using microsome supplementation in CHO cell-free system 2018 Biotechnology and Bioengineering · 115 · pp. 1253-1264 Chandrasekhar Gurramkonda, Aniruddha Rao, Shayan Borhani, Manohar Pilli, Sevda Deldari, Xudong Ge, Douglas D Frey, Govind Rao
  • Cell free expression of a therapeutic protein: expression, purification, and characterization of recombinant streptokinase using a CHO lysate 2018 Biotechnology and Bioengineering · 118 · pp. 92-102 Douglas D Frey, Kevin Tran, Chandrasekhar Gurramkonda, Merrideth Cooper, Manohar Pilli, Nicholas Selock, T.-C. Han, Michael Tolosa, Adil Zuber, Chariz Penalber, N. Pezeshk, Iordan V Kostov, Leah Tolosa, David Wood, Govind Rao

Creative Publications

  • Rapid and Low-Cost Sampling for Detection of Airborne SARS-CoV-2 in Dehumidifier Condensate 2021 Biotechnol. Bioeng. · 118 · pp. 3029-3036 P. Moitra, M. Alafeef, K. Dighe, P. Ray, Douglas D Frey, Dipanjan Pan, Govind Rao

Presentations

  • Application of Mechanistic Modeling for the Development of a Miniaturized Size Exclusion Chromatography (SEC) Column for on-Site Quantitative Analysis. 2025 AIChE Annual Meeting · AIChE · Oral Presentation Douglas D Frey, Govind Rao, Kadolkar Revati
  • Diffusion- Enhanced T-Flasks for Improved Cancel Cell Cultures 2025 SURF · UMBC · Poster Alexandria Slokan (Author & Presenter), Rishika Bandi (Author), Nathalie Tolosa (Author), Aaliyah Perez (Author), Abhay Andar (Author), Yunqian Wei (Author), Michael Tolosa (Author), Vikash Kumar (Author), Venkatesh Srinivasan (Author), Govind Rao (Author)
  • Next-Gen Breathable Shake Flasks for Improved Cell Growth and Real Time Monitoring 2025 SURF · UMBC · Poster Rishika Bandi (Author & Presenter), Vaishnavi Koralla (Author), Sravika Bolla (Author), Neveen Faris (Author), Vikash Kumar (Author), Michael Tolosa (Author), Venkatesh Srinivasan (Author), Govind Rao (Author)
  • Development of a Novel Analytical Sensor Utilizing Ni-NTA and His-tag Affinity for At-Line Quantitative Analysis of Binding Proteins. 2024 UMBC College of Engineering and Information Technology (COEIT) Research Day · UMBC · Poster Douglas D Frey, Govind Rao (Author), Vikash Kumar (Author), Revati Kadolkar (Author & Presenter)
  • Application of Mechanistic Modeling for the Understanding of Tailing in High Performance Liquid Chromatography (HPLC). 2024 UMBC Graduate Experience, Achievements & Research Symposium (GEARS) Research Symposium · UMBC · Poster Douglas D Frey (Author), Govind Rao (Author), Revati Kadolkar (Author & Presenter)
  • Affordable Hand-held Portable Spectroscopy Technology for PAT applications 2024 IFPAC · Poster Tithi Prajapati (Author & Presenter), Mike Tolosa (Author), Venkatesh Srinivasan (Author), Govind Rao (Author)
  • Polymer Carbon composite for wearable transcutaneous CO2 sensor 2024 IFPAC · Poster Mesha Mahajan (Author & Presenter), Preety Ahuja, Mike Tolosa (Other), Venkatesh Srinivasan (Author), Sanjeev Kumar (Author), Pegah Rezaei (Author), Govind Rao (Author)
  • Development of a novel analytical sensor utilizing Ni-NTA and His-tag affinity for at-line measurement of binding proteins. 2024 International Foundation for Process Analytical Chemistry (IFPAC) · International Foundation for Process Analytical Chemistry (IFPAC) · Poster Douglas D Frey (Author), Govind Rao (Author), Vikash Kumar (Author), Revati Kadolkar (Author & Presenter)
  • A Biosustainable Microfluidic Electrochemical Sensor for Real-time Monitoring of Nitrate in Groundwater and Streams 2023 Maryland Water Monitoring Council Annual Conference (MWMC) 30th Annual Conference · Maryland Water Monitoring Council Annual Conference (MWMC) · Poster Revati Kadolkar (Author & Presenter), Sai Kiran Mani (Author), Tithi Prajapati (Author), Preety Ahuja (Author), Mike Tolosa (Author), Venkatesh Srinivasan (Author), Sanjeev Kumar (Author), M McWilliams, Claire Welty, Govind Rao (Author)
  • Low-Cost, Next-Generation Optical Nitrate Sensor for Environmental Water Monitoring 2023 ABRCMS · Poster Tithi Prajapati (Author & Presenter), Sai Kiran Mani (Author), Mike Tolosa (Author), Venkatesh Srinivasan (Author), Govind Rao (Author)
  • Polymer carbon composite for wearable trancutaneous CO2 sensor 2023 ABRCMS · Poster Mesha Mahajan (Author & Presenter), Preety Ahuja (Author), Mike Tolosa (Author), Venkatesh Srinivasan (Author), Sanjeev Kumar (Author), Pegah Rezaei, Govind Rao (Author)
  • Application of mechanistic modeling for the understanding of tailing in HPLC 2023 IFPAC annual meeting · IFPAC · Poster Douglas D Frey (Author), Govind Rao (Author), Revati Kadolkar (Author & Presenter)

Grants and Contracts

  • Fair-Check: Bridging Racial Disparity with Novel, Non-invasive Device for Breast Cancer Self-Check 2025 UM-BILD · Grant · Funded Venkatesh Srinivasan (Principal), Pegah Rezaei (Co-Principal), Xudong Ge (Co-Principal), Govind Rao (Co-Principal)
  • VIRtua: Virus In-Line Rapid Testing with Ultrasensitive Assays 2025 Cytiva · Contract · Funded Govind Rao (Principal), Venkatesh Srinivasan (Co-Principal)
  • Smart Sensor for Non-invasive Monitoring of DO in shake flask cultures 2025 Alex Brown Center for Entrepreneurship, UMBC · Grant Venkatesh Srinivasan (Principal), Govind Rao (Co-Principal)
  • NitraSense: A portable water quality analyzer 2024 Maryland Technology Development Corporation (TEDCO) · Grant · Funded Venkatesh Srinivasan (Co-Principal), Govind Rao (Co-Principal), Sanjeev Kumar (Principal)
  • BLT bioreactors FDA · Grant · Currently Under Review Venkatesh Srinivasan (Principal), Xudong Ge (Co-Principal), Govind Rao (Co-Principal)
  • Evaluation of Griffithsin-based nanoparticles as universal secondary detector conjugates for virus detection NIH · Grant · Currently Under Review Venkatesh Srinivasan, Govind Rao (Co-Principal), Xudong Ge (Co-Principal)

Research in Progress

  • Novel sensor based handheld device for early detection of breast cancer 2025 Scholarly · On-Going Venkatesh Srinivasan, Govind Rao
  • “BreathShake”: Next-Generation Breathable Shake Flask 2025 Scholarly · On-Going Venkatesh Srinivasan, Govind Rao, Xudong Ge
  • Electrochemical sensors for environmental monitoring 2023 Scholarly · On-Going Sanjeev Kumar, Govind Rao, Preety Ahuja, Venkatesh Srinivasan

Patents and Intellectual Property

  • Factory-on-a-chip for production of biologically derived medicines/biopharmaceuticals/biologics/biotherapeutics 2025 Patent · No. US Patent 12,410,390 Douglas D Frey, Govind Rao, Iordan V Kostov, Sevda Deldari
  • System and method for production of on-demand proteins in a portable unit for POC delivery 2025 Patent · No. US 12,221,603 B2 Govind Rao, Iordan V Kostov, Leah Tolosa, Xudong Ge, Douglas D Frey
  • System and method for production of on-demand proteins in a portable unit for POC delivery 2024 Patent · No. 16/660,993 Douglas D Frey, Govind Rao, Iordan V Kostov, Leah Tolosa, Xudong Ge
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