Professor Katherine L Radtke PhD

Professor · Tenured

Department of Chemistry & Biochemistry

College of Natural and Mathematical Sciences

She/Her/Hers/Herself

Research interests

Synthetic organic/medicinal chemistry and drug design and development.

Teaching interests

Medicinal Chemistry

Education

  • Ph D, Organic Chemistry — Auburn University (1996)
    Carbocyclic Nucleosides in Medicinal Agent Design
  • BA, Organic Chemistry — University of South Florida (1992)
  • Other, Chemistry — St. Petersburg College (1983)
  • , Biology — Pennsylvania State University (1977)
  • , Biology — Gannon University (1976)

Publications

  • Flexible nucleobase analogues. New tools for nucleic acid discoveries 2014 RNA Technologies: DNA and RNA Chemical Biology in Science and Medicine · Springer · pp. 149-165 Sarah C Zimmermann, Katherine L Radtke

Presentations

  • Synthesis of flexible purine analogue inhibitors of NCp7 2014 7th Frontiers at the Chemistry and Biology Interface Symposium · UMBC, UMB, JHU, UMD-CP, U of Del · Poster Therese Ku (Author & Presenter), Hannah Peters (Author), Mattia Mori (Author), Maurizio Botta (Author), Katherine L Radtke (Author)
  • Adventures in Science, Policy and Diplomacy 2013 Women Chemists Dinner · Maryland Chapter, ACS · Keynote/Plenary Address
  • Adventures in Science, Policy and Diplomacy 2013 University of Notre Dame · Seminar
  • Exploiting the Nucleobase Scaffold for Drug Design and Diversity 2013 Medical University of South Carolina · Seminar
  • Exploring Structural Diversity in Nucleoside Drug Design 2013 FEBS Congress · FEBS · Lecture
  • Flexible Carbocylic Nucleosides: Design, Synthesis and Preliminary Biological Results 2013 Sixth Frontiers at the Chemistry and Biology Interface Symposium · UMBC, UMB, JHU, UMD-CP, U of Del · Poster Sarah C Zimmermann (Author & Presenter), Joshua M Sadler (Author), Peter I O'Daniel (Author), Elizaveta O'Neill (Author), Katherine L Radtke (Author)
  • Synthesis of Carbocyclic Nucleosides 2013 URCAD · UMBC · Poster Kelin Brace (Author & Presenter), Hannah Peters (Author), Katherine L Radtke (Author)
  • Synthesis of Cyclic and Acyclic Nucleotide Viral Polymerase Inhibitors 2013 URCAD · UMBC · Poster Brian Brown (Author & Presenter), Hannah Peters (Author), Katherine L Radtke (Author)
  • Adventures in Science, Policy and Diplomacy 2013 Salisbury State University · Seminar
  • Diversity in Nucleic Acids 2013 Look Ahead Symposium · UMBC · Poster Katherine L Radtke (Author), Sarah C Zimmermann (Author), Hannah L Peters (Author & Presenter), Therese Ku (Author & Presenter), Sadika Maharjan (Author & Presenter), Lauren Resch (Author & Presenter), Zhe Chen (Author)

Grants and Contracts

  • Graduate Training at the Chemistry Biology Interface 2019 DHHS,Dept of Health & Human Serv 93.000 · Grant · Funded
  • Discovery and development of halogenated purine analogues with potent anti-cancer activity 2015 NIH · Grant · Currently Under Review
  • Small molecule non-zinc ejector inhibitors of HIV and NCp7 2015 NIH · Grant · Funded
  • Track 1 Acquisition of a 500 MHz NMR System for Chemical Sciences Research and Training at the University of Maryland Baltimore County NSF · Grant · Not Funded Marcin Ptaszek (Principal), Marie-Christine Onuta (Co-Principal), Katherine L Radtke (Co-Principal)

Patents and Intellectual Property

  • Thieno- and Pyrrolopyrimidine Analogues as Anticancer Agents and methods of use thereof 2018 Patent · No. 10,561,658
  • Thieno- and Pyrrolopyrimidine Analogues as Anticancer Agents 2016 Patent · No. U.S. Patent 9,434,742 B1
  • Flexible Nucleoside Analogues as Antiviral Therapeutics 2015 Patent · No. 2013-0027KR