Dr. Liang Zhu

Research interests

Biotransport

Teaching interests

Thermal/fluid

Education

  • Ph D, Engineering — City University of New York (1995)
  • BS, Engineering Thermophysics — University of Science and Technology of China (1988)

Publications

  • Therapeutic Hypothermia for Neurological Injuries: Balancing Neuroprotection with Risks 2026 Molecular, Cellular, and Tissue Engineering in Vascular System · Springer · pp. 373-398
  • Performance characterization of non-contact infrared thermometers (NCITs) for forehead temperature measurement 2021 Medical Engineering and Physics · 93 · pp. 93-99 Stacey Sullivan, Nathanael Seay, Liang Zhu, Jean Rinaldi, Prasanna Hariharan, Oleg Vesnovsky, L D Topoleski
  • Effect of Surface Topography on Particle Deposition from Liquid Suspensions in Channel Flow 2020 Fluids · 4 (ISSN 2311-5521) · pp. 8 Myo Min Zaw, Liang Zhu, Ronghui Ma
  • Use of Piezoelectric Material for Advanced and Cost-Effective Tumor Screening. 2019 ASME 2018 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS), San Antonio, TX, September 10–12, 2018 · pp. SMASIS-2018-7957 Lucas McCullum, Liang Zhu, Soobum Lee
  • Nanoparticle Redistribution in PC3 Tumors Induced by Local Heating in Magnetic Nanoparticle Hyperthermia: In Vivo Experimental Study. 2019 ASME Journal of Heat Transfer · 141 (3) · pp. 032402 (1-9) Qimei Gu, T. Joglekar, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • Improvement of Student Retention and Graduation via Integration of Research into Education. 2018 2018 Transforming STEM Higher Education, Atlanta, November 8-10, 2018, . · pp. Paper number 74 Liang Zhu, Charles D Eggleton, Carlos Romero-Talamas, Dwayne D Arola, Anne M Spence
  • Hypothermia Used in Medical Applications for Brain and Spinal Cord Injury Patients. 2018 Molecular, Cellular, and Tissue Engineering in Vascular System · Springer · pp. 295-319
  • FABRICATION OF A CELL CULTURE PLATE WITH A 3D PRINTED MOLD AND THERMAL ANALYSIS OF PDMS-BASED CASTING PROCESS 2018 Journal of Thermal Science and Application · 10 · pp. 061002 Myo Min Zaw, Liang Zhu, Ronghui Ma
  • Feasibility of Visualization and Analyses of Deposition of Newly Developed Dendritic Ligand-Coated Gold Nanoparticles in PC3 Tumors Using MicroCT Scan 2018 ASME 2018 NanoEngineering for Medicine and Biology Conference, Los Angeles, August 21-24, 2018 · pp. NEMB2018-6181 Qimei Gu, A. Ray, Myo Min Zaw, Marie-Christine Onuta, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • In vitro study of transvascular transport of nanostructures using a 3D printed microfluidic platform 2018 ASME 2018 NanoEngineering for Medicine and Biology Conference, Los Angeles, August 21-24, 2018 · pp. NEME2018-6126. Myo Min Zaw, Jordan Bedler, Qimei Gu, Marie-Christine Onuta, Ronghui Ma, Liang Zhu
  • Improved Whole Body Heat Transfer Model for Determining Time of Death in Forensic Science 2018 8th World Congress of Biomechanics, Dublin, Ireland, July 8-12, 2018 · pp. WBC-2018-173 Ashley Wayne, Liang Zhu
  • Magnetic Nanoparticle Hyperthermia in Cancer Treatment: History, Mechanism, Imaging-Assisted Protocol Design, and Challenges 2018 Alexander LeBrun, and Liang Zhu · John Wiley & Sons, Entitled: Theory and Application of Heat Transfer in Cells and Organs- Alexander LeBrun, Liang Zhu
  • Investigation of biotransport in a tumor with uncertain material properties using a non-intrusive spectral uncertainty quantification method. 2017 ASME Journal of Biomechanical Engineering · 139 · pp. 091006 (1-11) Alan Alexanderia, Liang Zhu, Salloum Maher, Ronghui Ma, Meilin Yu
  • Gold Nanoparticle Based Laser Photothermal Therapy 2017 Manuchehrabadi, N., Zhu, L.. Handbook of Thermal Science and Engineering, Section: Heat Transfer in Biology and Biological Systems, · Springer, New York · pp. 1-32 Navid Manuchehrabadi, Liang Zhu
  • Using microCT to visualize nanofluid droplet sorption profiles in unsaturated powder beds. , in press, 2017. 2017 Munuhe, T., LeBrun, A., Zhu, L., and Ma, R.. · Powder Technology · 305 · pp. 232-240 Timothy Munuhe, Alexander LeBrun, Liang Zhu, Ronghui Ma
  • IMAGING-ASSISTED INDIVIDUAL DESIGNS OF HEATING PROTOCOLS FOR PROSTATIC TUMORS IN MAGNETIC NANOPARTICLE HYPERTHERMIA, 2017 2017 Annual Meeting of the Society for Thermal Medicine. , Cancun, Mexico, April 2017. · pp. Paper #: 0032 Alexander LeBrun, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • Treatment efficacy for validating microCT based theoretical simulation approach in magnetic nanoparticle hyperthermia for cancer treatment 2017 Alexander LeBrun, Tejashree Joglekar, Charles Bieberich, Ronghui Ma, and Liang Zhu · ASME Journal of Heat Transfer · 139 · pp. 051101(1-7) Alexander LeBrun, Tejashree Joglekar, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • Modeling of Differences between Body Core and Forehead Temperatures Measured by Infrared Thermometers. 2017 Vesnovsky, O., Li, Y., Topoleski, L. D. T., and Zhu, L.. · ASME 2017 Design of Medical Devices Conference, #DMD2017-3439, April 2017, Minneapolis, MN. Oleg Vesnovsky, Yiyong Li, L D Topoleski, Liang Zhu
  • Using microCT to visualize nanofluid droplet sorption profiles in unsaturated porous media. 2016 Munuhe, T., LeBrun, A., Zhu, L., and Ma, R.. · ASME 2016 Heat Transfer Conference, Washington DC, USA, paper number # HT2016-7325. Liang Zhu, Ronghui Ma, Timothy Munuhe
  • Determination of Time of Death in Forensic Science via a 3-D Whole Body Heat Transfer Model 2016 Catherine Bartgis, Alexander M LeBrun, Ronghui Ma, and Liang Zhu · Journal of Thermal Biology · 62 · pp. 109-115 Catherine Bartgis, Alexander LeBrun, Ronghui Ma, Liang Zhu
  • Investigation of Biotransport in a Tumor with Non-Homogeneous Permeability Using A Non-Intrusive Polynomial Chaos Approach. 2016 Lu, M., Salloum, M., Zhu, L., Ma, R., and Yu, M.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, National Harbor, MD, 2016. Paper number SB3C-2016-786. Miao Lu, Maher Salloum, Liang Zhu, Ronghui Ma, Meilin Yu
  • Evaluation of Sensitivity and Accuracy of Infrared Thermography for Melanoma Screening. 2016 Li, Y., LeBrun, A., Topoleski, L. D. T., and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, National Harbor, MD, 2016. Paper number SB3C-2016-145. Yiyong Li, Alexander LeBrun, L D Topoleski, Liang Zhu
  • Performance Evaluation of a Developed Acoustic Impedance Device in Tumor Screening. 2016 Mohammadabadi, A., Gu, Q., LeBrun, A., Younis, M., and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, National Harbor, MD, 2016. Paper number SB3C-2016-890. Ali Mohammadabadi, Qimei Gu, Alexander LeBrun, Mohamed F Younis, Liang Zhu
  • Recruiting and Supporting Transfer students to Mechanical Engineering Program at UMBC. 2016 Zhu, L., Arola, D., Spence, A., Romero-Talamas, C., and Eggleton, C.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, National Harbor, MD, 2016. Paper number SB3C-2016-23. Liang Zhu, Dwayne D Arola, Anne M Spence, Charles D Eggleton, Carlos Romero-Talamas
  • Validation of Image-assisted Modeling Approach to Design Heating Protocols in Magnetic Nanoparticle Hyperthermia. 2016 LeBrun, A., Joglekar, T., Bieberich, C., Ma, R., and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, National Harbor, MD, 2016. Paper number SB3C-2016-24. Alexander LeBrun, T Joglekar, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • Evaluating Accuracy of Digital Thermometers Using a Tissue Phantom Mimicking Normal and Fever Environments. 2016 Vesnovsky, O., Zhu, L., Casamento, J. P., Grossman, L. W., and Topoleski, L. D. T.. · ASME Journal of Medical Devices · 10 (2) · pp. 020913 (1-3) Oleg Vesnovsky, Liang Zhu, Jon P Casamento, Larry W Grossman, L D Topoleski
  • Evaluating Accuracy of Digital Thermometers Using a Tissue Phantom Mimicking Normal and Fever Environments. 2016 Vesnovsky, O., Zhu, L., Casamento, J. P., Grossman, L. W., and Topoleski, L. D. T.. · ASME 2016 Design of Medical Devices Conference, #DMD2016-8345, April 2016, Minneapolis, MN. Oleg Vesnovsky, Liang Zhu, Jon P Casamento, Larry W Grossman, L D Topoleski
  • Identification of Infusion Strategy for Achieving Repeatable Nanoparticle Distribution and Quantifiable Thermal Dosage in Magnetic Nanoparticle Hyperthermia. , 2016 LeBrun, A., Joglekar, T., Bieberich, C., Ma, R. and Zhu, L.. I · International Journal of Hyperthermia · 32 (2) · pp. 132-143 Alexander LeBrun, Tejashree Joglekar, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • Tumor Shrinkage Study in Magnetic Nanoparticle Hyperthermia Based on Designed Heating Protocols. 2016 LeBrun, A., Ma, R., and Zhu, L. · ASME 2016 5th Micro/Nanoscale Heat and Mass Transfer International Conference, Singapore, 2016. Alexander LeBrun, Ronghui Ma, Liang Zhu
  • Tumor Shrinkage Study in Magnetic Nanoparticle Hyperthermia Based on Designed Heating Protocols. . 2016 LeBrun, A., Ma, R., and Zhu, L. · ASME 2016 5th Micro/Nanoscale Heat and Mass Transfer International Conference, Singapore, 2016 Alexander LeBrun, Ronghui Ma, Liang Zhu
  • Numerical study of turbulent gas flow and CO2 absorption in porous media. 2015 Patil, A., Wang, F., Zhu, L., and Ma, R.. · Proceedings of the 1st Thermal and Fluid Engineering Summer Conference, TFESC, August 9-12, 2015, New York City, USA, paper number #TFESC-12861.
  • Evaluation accuracy of the algorithm/formula used in store brand digital thermometers to predict body temperature based on the first few seconds of the temperature measurements. 2015 Saharhkiz, A., Vesnovsky, O., Casamento, J. P., Grossman, L. W., Topoleski, L., and Zhu, L.. · Summer Bio mechanics, Bioengineering, & Biotransport Conference, Snowbird, Utah, June 2015, paper number #15-A-507-SB3C.
  • Development of a tissue phantom to mimic the thermal environment of a human arm to test digital thermometers. . 2015 Dillon, P., Vesnovsky, O., Topoleski, L., Casamento, J. P., Grossman, L. W., and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, Snowbird, Utah, June 2015, paper number #15-A-501-SB3C
  • Feasibility of utilizing thermal images for melanoma screening. 2015 LeBrun, A. and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, Snowbird, Utah, June 2015, paper number #15-A-126-SB3C.
  • Generating tumor models from microCT scan images for simulating temperature elevation during magnetic nanoparticle hyperthermia. . 2015 Lee, A. S., LeBrun, A., Ma, R., and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, Snowbird, Utah, June 2015, paper number #15-A-300-SB3C
  • Imaging processing algorithms for detecting subtle morphological changes in mole images over time. 2015 Chamani, A. Nathan, N., Hornyak, T., and Zhu L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, Snowbird, Utah, June 2015, paper number #15-A-235-SB3C.
  • Numerical and experimental study of colloidal droplet impact and sorption in porous substrate. 2015 Munuhe, T., LeBrun, A., Li, K., Zhu, L., and Ma, R.. · Proceedings of the 1st Thermal and Fluid Engineering Summer Conference, TFESC, August 9-12, 2015, New York City, USA, paper number #TFESC-12858.
  • Strategies of injecting ferrofluid into tumors to achieve repeatable nanoparticle deposition and thermal dosage in magnetic nanoparticle hyperthermia. 2015 LeBrun, A., Bieberich, C., Ma, R., and Zhu, L.. · Summer Biomechanics, Bioengineering, & Biotransport Conference, Snowbird, Utah, June 2015, paper number #15-A-286-SB3C.
  • Dynamic thermal interaction between arterial blood and tissue temperatures in developing a whole body heat transfer model. 2014 7th world Congress of Biomechanics, abstract #2201, July 2014, Boston, MA.

Presentations

  • Study of stability, toxicity and cellular localization of dendronized gold nanoparticles for in vivo (MCF-7) and in vivo xenograft (PC-3) mice models 2018 Frontiers in Chemistry and Biology Interface Symposium · University of Pennsylvanya · Poster Arunendra Saha Ray (Author & Presenter), Y. J Pak (Author), Q. Gu (Author), T. Joglekar (Author), M. M Zaw (Author), Charles Joseph Bieberich (Author), Liang Zhu (Author), Peter Swaan (Author), Marie-Christine Daniel (Author)
  • Imaging-assisted individual designs of heating protocols for prostatic tumors in magnetic nanoparticle hyperthermia 2017 Research Seminar in the National Engineering Research Center for Biomaterials · Sichuan University, China · Seminar
  • Nanoparticle re-distribution in tissue-equivalent gels induced by magnetic nanoparticle hyperthermia 2017 Summer Biomechanics, Bioengineering, and Biotransport Conference · ASME · Poster Qimei Gu (Author & Presenter), Myo Zaw (Author), Tim Munuhe (Author), Ronghui Ma (Author), Liang Zhu (Author)
  • Imaging-assisted individual designs of heating protocols for prostatic tumors in magnetic nanoparticle hyperthermia 2017 34th Annual Meeting of The Society for Thermal Medicine · Society for Thermal Medicine · Oral Presentation Alexander LeBrun (Author), Charles Joseph Bieberich (Author), Ronghui Ma (Author), Liang Zhu (Author & Presenter)
  • Nanoparticle Hyperthermia 2016 UMBC50 Celebration · UMBC · Oral Presentation
  • S-STEM Programs for Engineering and Computing Transfer Students 2015 22nd National Conference on Students in Transition · National Resource Center for the First Year Experience and Students in Transition · Oral Presentation
  • I presented five papers in the conference with my students. 2015 S3BC conference · ASME · Oral Presentation

Grants and Contracts

  • Using Stealth Nanocarriers with Mild Whole-body Hyperthermia to Enhance Co-delivery of Multiple Chemotherapeutics in Prostate Tumors 2026 DoD · Grant · Not Funded Marie-Christine Onuta, Charles Joseph Bieberich (Co-Principal), Liang Zhu (Co-Principal)
  • Refreshable Braille Display with Tactile Magnetic Pulse 2025 UMBC · Grant · Funded Alok Ghanekar (Principal), Liang Zhu (Co-Principal)
  • Remotely operated intraoral camera system with precision control 2023 UMBC · Grant · Funded Ankit Goel (Principal), Liang Zhu (Co-Principal)
  • Particulate fouling behavior on physically modified surfaces 2020 American Chemical Society · Grant · Not Funded Liang Zhu (Co-Principal), Ronghui Ma (Principal)
  • Collaborative Research: Physics-driven stochastic modeling for tumor structure inversion from in vivo experimental data 2019 National Science Foundation · Grant · Not Funded Liang Zhu (Co-Principal), Meilin Yu (Principal), Charles Joseph Bieberich (Co-Principal)
  • Strengthening Pipeline of Woman Engineers through Research Exposure and Mentoring: A Project for Promoting Community College Students to Transfer to 4 Year Institutions 2019 Engineering Information Foundation · Grant · Not Funded Liang Zhu (Principal), Ronghui Ma (Co-Principal), Shuyan Sun (Co-Principal)
  • Recruitment, Engagement, and Retention: Energizing and Supporting Students with Diverse Backgrounds in Mechanical Engineering 2018 NSF · Grant · Funded Liang Zhu (Principal), Charles D Eggleton (Co-Principal), L D Topoleski (Co-Principal), Deepa Madan (Co-Principal), Ronghui Ma (Co-Principal)
  • Mild hyperthermia to enhance delivery of therapeutic nanocarriers in tumors: imaging, in vivo study, and simulation 2017 NSF · Grant · Funded Liang Zhu (Principal), Ronghui Ma (Co-Principal), Charles Joseph Bieberich (Co-Principal)
  • Novel transRectal Focal Abdominal Cooling (rFAC) REBOA for the Treatment of Organ Ischemia-Reperfusion Injury (IRI) 2017 UMBC, UMB · Grant · Not Funded Liang Zhu (Principal), Bingren HU (Principal), Ronghui Ma (Co-Principal)
  • Sensory perception of e-cigarette inhalants and associated long-term alteration in the nervous systems 2017 UMBC · Grant · Not Funded Liang Zhu (Co-Principal), Weihong Lin (Principal), Ronghui Ma (Co-Principal)
  • Determination of heterogeneous transport properties of tumors using spectral uncertainty quantification methods 2017 NIH-R21 · Grant · Not Funded Liang Zhu (Co-Principal), Meilin Yu (Principal)
  • A Low Cost Breast Cancer Screening Device Using Piezoelectricity - Development and Evaluation 2017 NIH-R21 · Grant · Not Funded Liang Zhu (Principal), Soobum Lee (Co-Principal)
  • A low-cost and portable breast cancer detection device for early stage screening 2016 DoD · Grant · Not Funded Liang Zhu (Co-Principal), Soobum Lee (Principal)
  • Assessing the Accuracy of Commercial Non-Contact Infrared Thermometers for Detecting Fever – Clinical Study 2016 FDA · Contract · Not Funded Liang Zhu (Co-Principal), L D Topoleski (Principal)
  • Investigation of nanofluid droplet interactions with powder bed for improving three-dimensional printing capabilities 2016 NSF · Grant · Not Funded Liang Zhu (Co-Principal), Ronghui Ma (Principal)
  • Selective Brain Cooling and Temperature Monitoring Device 2016 DoD/N2Biomedical · SubContract · Not Funded
  • Infrared Thermal Imaging of Breast Cancer Tumors Enhanced by Ultrafast One and Two-Photon Fluorescence and Raman Scattering 2016 DoD · Grant · Not Funded
  • Development of a 3-D whole body heat transfer model for accurately predicting time of death in forensic Science 2016 UMBC · Grant · Not Funded
  • Evaluation of accuracy of commercial non-contact infrared thermometers for detecting fever 2015 FDA · Contract · Funded Liang Zhu (Co-Principal), L D Topoleski (Principal)
  • Development of a Multi-Organ Fluidic Platform for Evaluation of a Novel Therapeutic Regimen for Leukemia Chemotherapy 2015 Umbc - Umab · Grant · Funded Ronghui Ma (Principal), Liang Zhu (Co-Principal)
  • Diversification and Retention: Creating New Paths of Success for STEM Scholars in Mechanical Engineering 2014 NSF · Grant · Funded Liang Zhu (Principal), Dwayne Arola (Co-Principal), Charles Eggleton (Co-Principal), Carlos Romero-Talamas (Co-Principal), Anne Spence (Co-Principal)
  • “Development of a prototype design of a testing apparatus to verify accuracy of medical digital thermometers in predictive mode” 2013 FDA · Contract · Funded LD Timmie Topoleski (Co-Principal), Liang Zhu (Principal)
  • “Developing a test method to verify accuracy of medical digital thermometers 2012 FDA · Contract · Funded L D Topoleski (Co-Principal), Liang Zhu (Principal)
  • Development of an Accurate Heat Transfer Model 1999 The Whitaker Foundation · Grant · Funded

Patents and Intellectual Property

  • Remotely operated intraoral camera system with precise control 2025 Disclosure · No. UMBC-41885.103 Ankit Goel, Liang Zhu
  • Development of a Refreshable Braille Display System with Tactile Magnetic Pulses 2024 Disclosure · No. UMBC Alok Ghanekar, Liang Zhu
  • Remotely operated intraoral camera system with precise control 2024 Disclosure · No. UMBC-41885.10 Ankit Goel, Liang Zhu
  • Remotely operated intraoral camera system with precise control 2023 Disclosure · No. UMBC-41885.10 Ankit Goel, Liang Zhu
  • Development of a Whole Body Thermal Model to Determine Time of Death 2015 Disclosure · No. 2015-015