Dr. Marie-Christine Onuta

Associate Professor · Tenured

Department of Chemistry & Biochemistry

College of Natural and Mathematical Sciences

About

She obtained her PhD degree in Chemistry from University of Bordeaux 1 (France).
She carried out some postdoctoral research, focused on inorganic nanoparticles, at Indiana University, Bloomington.

Research interests

Drug delivery of chemotherapeutics
Prostate cancer
Construction of hybrid nanomaterials
Nanotheranostics

Teaching interests

Inorganic chemistry
Nanoparticles

Education

  • Ph D, Organometallic chemistry — University of Bordeaux 1 (2003)

Publications

  • Directed Assembly of Gold Bipyramids and Quantum Dots via Click Chemistry for Plasmon-Exciton Coupling 2025 ACS Applied Nano Materials · 8 (39) · pp. 18751-18761 Marie-Christine Onuta, Matthew A Pelton, Tohid Baradaran Kayyal, Vijin Kizhake Veetil, Reshma Mathew, Lekan Ajiboye, Chanda Lowrance
  • Single Nanomaterial Level Investigation of ZnO Nanorod Sulfidation Reaction via Position Resolved Confocal Raman Spectroscopy 2019 Nanoscale · 11 · pp. 1147-1158 Matthew Hansen, Johnson Truong, Brian Szychowski, Tian Xie, Marie-Christine Daniel, Jong-in Hahm
  • Controlled etching and tapering of Au nanorods using cysteamine 2018 Nanoscale · 10 (35) · pp. 16830=16838 Brian Szychowski, Haixu Leng, Matthew A Pelton, Marie-Christine Daniel
  • Feasibility of Visualization and Analyses of Deposition of Newly Developed Dendritic Ligand-Coated Gold Nanoparticles in PC3 Tumors Using MicroCT Scan 2018 ASME 2018 NanoEngineering for Medicine and Biology Conference, Los Angeles, August 21-24, 2018 · pp. NEMB2018-6181 Qimei Gu, A. Ray, Myo Min Zaw, Marie-Christine Onuta, Charles Joseph Bieberich, Ronghui Ma, Liang Zhu
  • In vitro study of transvascular transport of nanostructures using a 3D printed microfluidic platform 2018 ASME 2018 NanoEngineering for Medicine and Biology Conference, Los Angeles, August 21-24, 2018 · pp. NEME2018-6126. Myo Min Zaw, Jordan Bedler, Qimei Gu, Marie-Christine Onuta, Ronghui Ma, Liang Zhu
  • Dendronized Systems for the Delivery of Chemotherapeutics 2018 Cancer Nanotechnology · Elsevier · 139 (1st edition) · pp. 85-114 Lance Dockery, Marie-Christine Daniel
  • Spatially Correlated, Single Nanomaterial-Level Structural and Optical Profiling of Cu-Doped ZnO Nanorods Synthesized via Multifunctional Silicides 2018 Nanomaterials · 8 · pp. 222 Johnson Truong, Matthew Hansen, Brian Szychowski, Tian Xie, Marie-Christine Daniel, Jong-in Hahm
  • Design and characterization of crotamine-functionalized gold nanoparticles 2018 COLLOIDS AND SURFACES B-BIOINTERFACES · 163 · pp. 1-8 R L Karpel, Michelle da Silva Liberato, Joana D Campeiro, Lorna Bergeon, Brian Szychowski, Andrew Butler, Giovanni Marino, Joelle F Cusic, Lilian C Goncalves de Oliveira, Eduardo B Oliveira, Marcelo Alexandre de Farias, Rodrigo V Portugal, Wendel A Alves, Marie-Christine Daniel, Mirian A. F Hayashi

Presentations

  • Dual Role of Dendronized Gold Nanoparticles as both Catalyst and Drug-Loading Core in the Formation of Gold Nanorattles 2025 International Conference Gold 2025 · Oral Presentation Marie-Christine Daniel (Author & Presenter), Tohid Baradaran-Kayyal (Author), Taylor Thorsen (Author), Michael Marciniak (Author)
  • Directed Formation of Gold Nanobipyramids/quantum dots trimer for quantum technology application 2025 2025 Graduate Experience Achievements Research Symposium · UMBC Graduate School · Poster Lekan Ajiboye (Author & Presenter), Reshma Mathew (Author), Chanda M Lowrance (Author), Tohid Baradaran Kayyal (Author), Matthew Pelton (Author), Marie-Christine Daniel (Author)
  • Directed Formation of Gold Nanobipyramids/quantum dots trimer for quantum technology application 2025 2025 UMBC Chemistry/Biochemistry Graduate Research Day · UMBC Department of Chemsitry and Biochemistry · Poster Lekan Ajiboye (Author & Presenter), Reshma Mathew (Author), Chanda M Lowrance (Author), Tohid Baradaran Kayyal (Author), Matthew Pelton (Author), Marie-Christine Daniel (Author)
  • Synthesis of a Stealth Dendron: PEGylated Ligand Design for Gold Nanoparticle Drug Delivery Applications 2025 2025 UMBC Chemistry/Biochemistry Graduate Research Day · UMBC Department of Chemsitry and Biochemistry · Poster Michael A Marciniak (Author & Presenter), Marie-Christine Daniel (Author)
  • Designing Gold Nanorattles Using Dendronized Gold Nanoparticles with Dual Role: Catalyst and Cargo-Carrying Core in Nanorattle Synthesis 2024 2024 UMBC Chemistry Graduate Research Day · UMBC Department of Chemistry and Biochemistry · Oral Presentation Tohid Baradaran Kayyal (Author & Presenter), Marie-Christine Daniel (Author)
  • Discrete Assembly of Gold Nano Bipyramids and CdSe/CdS Quantum Dots for Quantum Technology Applications 2024 2024 UMBC Chemistry Graduate Research Day · UMBC Department of Chemsitry and Biochemistry · Poster Lekan Ajiboye (Author & Presenter), Marie-Christine Daniel (Author)
  • From Liters to Milliliters: Synthesis of Highly Concentrated Prostate Cancer Targeting Gold Nanoparticles for High-Intensity Focused Ultrasound 2024 2024 UMBC Chemistry Graduate Research Day · UMBC Department of Chemsitry and Biochemistry · Poster Michael Marciniak (Author & Presenter), Marie-Christine Daniel (Author)
  • Dendronized gold nanoparticles for the targeted delivery of chemotherapeutic agents 2023 NanoDDS · Poster Marie-Christine Daniel, Arunendra Saha Ray, Lance T Dockery
  • Gold Nanoparticles for diagnostic and targeted HIFU treatment 2023 NanoDDS · Poster Michael Marciniak, Marie-Christine Daniel
  • Facile Single-Phase Method for Efficient Transfer of Oleic Acid Capped Nanoparticles from Organic to Aqueous Media 2023 UMBC Chemistry Graduate Research Day · UMBC Department of Chemistry and Biochemistry · Poster Tohid Baradaran Kayyal (Author & Presenter), Marie-Christine Onuta (Author)
  • Synthesis of Gadolinium (III) Bearing Dendron and Development of an MRI Contrast Agent Nanoplatform 2023 UMBC Chemistry Graduate Research Day · UMBC Department of Chemsitry and Biochemistry · Poster Michael Marciniak (Author & Presenter), Marie-Christine Onuta (Author)
  • Synthesis, Assembly, and Isolation of AuBP-QD-AuBP Trimers 2023 UMBC Chemistry Graduate Research Day · UMBC Department of Chemistry and Biochemistry · Poster Chanda M Lowrance (Author & Presenter), Marie-Christine Onuta (Author)
  • Dendronized Gold Nanoparticles for Cancer Therapy 2022 UMB · Seminar
  • Development of Inorganic Nanoparticles for Medical, Materials and Environmental Applications 2022 Global Summit on Nanotechnology and Materials Sciences · Oral Presentation
  • Targeted Dendronized Gold Nanoparticles for Stimuli-responsive Delivery of Doxorubicin 2022 Global Virtual Summit on Nanoscience & Nanotechnology · Oral Presentation
  • Dendronized Gold Nanoparticles for Targeted and Controlled Cancer Therapy. 2021 4th UMBC Chemistry and Biochemistry Graduate Research Day · UMBC Chemistry and Biochemistry Department · Poster Lance T Dockery (Author & Presenter), Marie-Christine Daniel (Author)
  • Multifunctional Nanocarriers for Cancer Therapy using Dendronized Gold Nanorattles. 2021 4th UMBC Chemistry and Biochemistry Graduate Research Day · UMBC Chemistry and Biochemistry Department · Poster Tohid Baradaran Kayyal (Author & Presenter), Marie-Christine Daniel (Author)
  • Controlled Formation of Silica on Noble Metal and Semiconducting Nanoparticles for Assembly via Siloxane Linkage 2020 3rd UMBC Chemistry and Biochemistry Graduate Research Day · UMBC Chemistry and Biochemistry Department · Poster Chanda M Lowrance (Author & Presenter), Marie-Christine Daniel (Author)
  • Dendronized Gold Nanorattle as a Platform for Drug Delivery. 2020 3rd UMBC Chemistry and Biochemistry Graduate Research Day · UMBC Chemistry and Biochemistry Department · Poster Tohid Baradaran Kayyal (Author & Presenter), Marie-Christine Daniel (Author)
  • Design and Synthesis of a Doxorubicin-PPI Dendron Conjugate Through Acid-labile Bonds. 2020 3rd UMBC Chemistry and Biochemistry Graduate Research Day · UMBC Chemistry and Biochemistry Department · Poster Lance T Dockery (Author & Presenter), Marie-Christine Daniel (Author)
  • Synthesis of a Gold Nanobipyramid–CdSe/CdS Quantum Dot Dimer via Amide Linkage 2019 2019 NOBCChE Meeting · NOBCChE · Poster Chanda M Lowrance (Author & Presenter), Marie-Christine Daniel
  • Synthesis of Silver Nanoparticle-Based Sensor for the Detection of Lead in Water 2019 SEED Research Symposium · ACS · Poster Kevin Hu (Author & Presenter), Chanda M Lowrance (Author), Marie-Christine Daniel
  • Synthesis and characterization of a doxorubicin-conjugated dendronized system for efficient and controlled delivery of cancer therapeutics 2019 50th MARM (Middle Atlantic Regional Meeting) · ACS · Oral Presentation Lance T Dockery (Author & Presenter), Marie-Christine Daniel
  • Design and Synthesis of a Doxorubicin-PPI Dendron Conjugate Through Acid-labile Bonds 2019 Cancer Nanotechnology GRC · GRC · Poster Lance T Dockery (Author & Presenter), Marie-Christine Daniel
  • Multifunctional inorganic nanoparticles for medical and materials applications 2019 50th MARM (Middle Atlantic Regional Meeting) · ACS · Oral Presentation
  • Synthesis of a Gold Nanobipyramid–CdSe/CdS Quantum Dot Dimer via Amide Linkage 2019 50th MARM (Middle Atlantic Regional Meeting) · ACS · Poster Chanda M Lowrance (Author & Presenter), Marie-Christine Daniel
  • Synthesis of Dendronized Gold Nanoparticles with Acid-labile Bonds for Controlled Delivery of Cancer Therapeutics 2019 256th ACS National Meeting · ACS · Poster Lance T Dockery (Author & Presenter), Marie-Christine Daniel
  • Coupling of Gold Nanobipyramid and CdSe/CdS Quantum Dot via Amide Linkage 2019 2nd UMBC Chemistry and Biochemistry Graduate Research Day · UMBC · Poster Chanda Lowrance (Author & Presenter), Haixu Leng (Author), Matthew A Pelton (Author), Marie-Christine Daniel (Author)
  • Design and Synthesis of a Doxorubicin-PPI Dendron Conjugate Through Acid-labile Bonds 2019 2nd UMBC Chemistry and Biochemistry Graduate Research Day · UMBC · Poster Lance Dockery (Author & Presenter), Marie-Christine Daniel (Author)
  • Relative Adsorption of Amine and Carboxylate Terminated PPI Dendrons to Gold Nanoparticles 2018 Summer Undergraduate Research Feast · UMBC · Poster Renee Suzich (Author & Presenter), Arunendra Saha Ray (Author), Marie-Christine Daniel
  • Study of stability, toxicity and cellular localization of dendronized gold nanoparticles for in vivo (MCF-7) and in vivo xenograft (PC-3) mice models 2018 Frontiers in Chemistry and Biology Interface Symposium · University of Pennsylvanya · Poster Arunendra Saha Ray (Author & Presenter), Y. J Pak (Author), Q. Gu (Author), T. Joglekar (Author), M. M Zaw (Author), Charles Joseph Bieberich (Author), Liang Zhu (Author), Peter Swaan (Author), Marie-Christine Daniel (Author)
  • Assembly of CdSe Quantum Dots and Gold Nanorods into Discrete Arrangements with Unique Optical Properties 2018 1st UMBC Chemistry and Biochemistry Graduate Research Day · UMBC · Poster Brian Szychowski (Author & Presenter), Haixu Leng (Author), Matthew A Pelton (Author), Marie-Christine Daniel (Author)
  • Investigation of Stability, Cytotoxicity and cellular Fate of PPI-dendronized –Gold Nanoparticles in MCF-7 Breast Cancer lines 2017 15th International Nanomedicine and Drug Delivery Symposium · Poster Arunendra Saha-Ray (Author & Presenter), Yweon Pak, (Author), Swaan Peter (Author), Marie-Christine Onuta

Grants and Contracts

  • Using Stealth Nanocarriers with Mild Whole-body Hyperthermia to Enhance Co-delivery of Multiple Chemotherapeutics in Prostate Tumors 2026 DoD · Grant · Not Funded Marie-Christine Onuta, Charles Joseph Bieberich (Co-Principal), Liang Zhu (Co-Principal)
  • Preparation and Manipulation of Quantum Dots with Increased Luminescence in Water 2023 NSF · Grant · Funded
  • Polymer Nanoparticle Composites with Enhanced Anti-Fouling and Surface-Adhesion Properties 2020 Maryland Institutional Partnerships · Grant · Not Funded Lisa A Kelly (Co-Principal), Marie-Christine Daniel-Onuta (Co-Principal)
  • Acquisition of a TEM NSF · Grant Marie-Christine Daniel (Co-Principal), Erin Lavik (Co-Principal), Marcus Zupan (Co-Principal), Tagide deCarvalho (Principal)
  • Chemoprevention of Basal-like Breast Cancer Development DoD · Grant · Not Funded Marie-Christine Onuta (Co-Principal), Qun Zhou (Principal)
  • Oncogenic LIPG and Breast Cancer NIH · Grant · Not Funded Marie-Christine Onuta (Co-Principal), Qun Zhou (Principal)
  • Palmitic Acid and Basal-like Breast Cancer Progression Veteran Affairs · Grant · Not Funded Marie-Christine Onuta (Co-Principal), Qun Zhou (Principal)
  • Supraphysiologic Nutrients and Fibroblast Differentiation NIH · Grant · Not Funded Marie-Christine Onuta (Co-Principal), Qun Zhou (Principal)
  • Targeting LIPG for Treatment of Triple-negative Breast Cancer Invasion DoD · Grant · Not Funded Marie-Christine Onuta (Co-Principal), Qun Zhou (Principal)
  • Track 1 Acquisition of a 500 MHz NMR System for Chemical Sciences Research and Training at the University of Maryland Baltimore County NSF · Grant · Not Funded Marcin Ptaszek (Principal), Marie-Christine Onuta (Co-Principal), Katherine L Radtke (Co-Principal)