Dr. Minjoung Kyoung

Associate Professor · Tenured

Department of Chemistry & Biochemistry

College of Natural and Mathematical Sciences

About

Dr. Kyoung earned her Ph.D. in 2008 from the Chemistry Department at the Pennsylvania State University. After a period as a postdoctoral scholar at the Stanford University and University of California, Berkeley, she joined the Chemistry and Biochemistry Department at the University of Maryland, Baltimore County (UMBC). Currently she is an Assistant Professor at UMBC.

Research interests

Our research focuses on developing and applying novel bioanalytical and biophysical tools to understand molecular underpinnings of how signaling pathways cross-talk with metabolic pathways in cancer cells. Two current projects include 1. the development of an advanced versatile nano-reaction chamber designed to detect transient protein-protein interactions in confined dimensions, and 2. the development of a novel super-resolution imaging technique to map critical biological networks in live cells. Ultimately, we aim to determine how signaling pathways are spatially and temporally involved in cancer cell development and proliferation by employing unprecedented in vitro and live cell techniques. In our lab, students are trained in cross-disciplinary research at the chemistry-biology-physics interface by building cutting edge microscopy/spectroscopy systems, fabricating nano-reaction chambers and flow cells, and studying the interactions between biomolecules in real time in vivo and in vitro.

Teaching interests

Quantitative Bio-imaging and AI image informatics
Quantitative Analytical Microscopy
Fundamentals of Light Microscopy
Analytical Chemistry
Advanced Analytical Methods
Advanced Instrumental Methods of Analysis

Education

  • Ph D, Chemistry — Pennsylvania State University (2008)
    Molecular dynamics of biomembrane as probed by multifaceted biophotonics

Publications

  • Mechanistic insights into condensate formation of human liver-type phosphofructokinase by stochastic modeling approaches 2024 Scientific Reports · 14 · pp. 19011 Hye-Won Kang, Luan Nguyen, Songon An, Minjoung Kyoung
  • Size-specific modulation of a multienzyme glucosome assembly during the cell cycle 2023 ACS Bio and Med Chem Au · 3 (5) · pp. 461-470 Miji Jeon, Danielle L Schmitt, Minjoung Kyoung, Songon An
  • High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme metabolic assembly in human cells 2023 PLoS One · 18 · pp. e0289707 Danielle L Schmitt, Patricia Dranchak, Prakash Parajuli, Dvir Blivis, Ty Voss, Casey L Kohnhorst, Minjoung Kyoung, James Inglese, Songon An
  • Multi-dimensional fluorescence live-cell imaging for glucosome dynamics in living human cells 2022 Methods in Molecular Biology Songon An, Prakash Parajuli, Erin L Kennedy, Minjoung Kyoung
  • Subcellular regulation of glucose metabolism through multienzyme glucosome assemblies by EGF-ERK1/2 signaling pathways 2022 Journal of Biological Chemistry · 298 · pp. 101675 Miji Jeon, Krishna M Chauhan, Gregory L Szeto, Minjoung Kyoung, Songon An
  • Functional oscillation of a multienzyme glucosome assembly during cell cycle progression 2022 bioRxiv Miji Jeon, Danielle L Schmitt, Minjoung Kyoung, Songon An
  • Phase-Separated Condensates of Metabolic Complexes in Living Cells: Purinosome and Glucosome 2019 Methods in Enzymology · 628 · pp. 1-17 Songon An, Miji Jeon, Erin L Kennedy, Minjoung Kyoung
  • Indentification of a Multienzyme Metabolic Complex in Living Cells 2017 Journal of Biological Chemistry · 292 · pp. 9191-9203 Casey L Kohnhorst, Minjoung Kyoung, Miji Jeon, Danielle L Schmitt, Erin L Kennedy, Julio Ramirez, Syrena M Bracy, Bao Tran Luu, Sarah J Russell, Songon An

Presentations

  • Role of Hypoxia in Glucosome Formation and Function in Cancer Cells 2026 ACS Middle Atlantic Regional Meeting 2026 · ACS · Poster Bijaya B.K. (Author & Presenter), Deepika Jaiswal (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Functional Contribution of Multienzyme Glucosome Condensates to Cellular Redox Homeostasis 2026 Graduate Research Day · University of Maryland, Baltimore County · Oral Presentation Ashesh Sharma (Author & Presenter), Bijaya B.K. (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Functional Contribution of Multienzyme Glucosome Condensates to Cellular Redox Homeostasis 2026 The Annual Frontiers at the Chemistry-Biology Interface Symposium · University of Maryland, Baltimore County · Poster Ashesh Sharma (Author & Presenter), Bijaya B.K. (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Role of Hypoxia in Glucosome Formation and Function in Cancer Cells 2026 The Annual Frontiers at the Chemistry-Biology Interface Symposium · University of Maryland, Baltimore County · Poster Bijaya B.K. (Author & Presenter), Deepika Jaiswal (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Role of Hypoxia in Glucosome Formation and Function in Cancer Cells 2026 Graduate Research Day · University of Maryland, Baltimore County · Poster Bijaya B.K. (Author & Presenter), Deepika Jaiswal (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Functional Contribution of Multienzyme Glucosome Condensates to Cellular Redox Homeostasis 2025 The Annual Frontiers at the Chemistry-Biology Interface Symposium · University of Maryland, Baltimore County · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Modulating size distribution of glucosomes to understand their size-dependent functional contributions to cellular redox homeostasis 2025 Graduate Research Day · UMBC · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Functional Contribution of Multienzyme Glucosome Condensates to Cellular Redox Homeostasis 2025 The 2025 Annual Biochemistry and Molecular Biology Retreat · University of Maryland, School of Medicine · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Dynamic Association of Multienzyme Glucosome Assemblies with the Cell Cycle in Human Cells 2024 The Gordon Research Conference: Enzymes, Coenzymes and Metabolic Pathways · The Gordon Research Conference · Poster Miji Jeon (Author), Danielle L Schmitt (Author), Minjoung Kyoung (Author), Songon An (Author & Presenter)
  • Modulating size distribution of glucosomes to understand their functional contributions to cellular redox homeostasis 2024 The Annual Frontiers at the Chemistry-Biology Interface Symposium · University of Maryland, Baltimore County · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Modulating size distribution of glucosomes to understand their size-dependent functional contributions to cellular redox homeostasis 2024 CNMS Graduate Research Festival · UMBC · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Modulating size distribution of glucosomes to understand their size-dependent functional contributions to cellular redox homeostasis 2024 Graduate Experience, Achievements & Research Symposium · UMBC · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Modulating size distribution of glucosomes to understand their size-dependent functional contributions to cellular redox homeostasis 2024 Graduate Research Day · UMBC · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Spatial Biochemistry of Glucose Flux Regulation by Multienzyme Glucosome Assemblies in Human Cells 2023 The Gordon Research Conference: Enzymes, Coenzymes and Metabolic Pathways · The Gordon Research Conference · Poster Miji Jeon (Author), Minjoung Kyoung (Author), Songon An (Author & Presenter)
  • Hyperosmotic stress alters enzyme composition rations of glucosomes 2023 The Annual Frontiers at the Chemistry-Biology Interface Symposium · University of Maryland, School of Pharmacy · Poster Haotian Wu (Author & Presenter), Spencer Jaquet (Author), Songon An (Author), Minjoung Kyoung (Author)
  • Modulating size distribution of glucosomes to understand their functional contributions to cellular redox homeostasis 2023 The Annual Frontiers at the Chemistry-Biology Interface Symposium · University of Maryland, School of Pharmacy · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Hyperosmotic stress alters enzyme composition rations of glucosomes 2023 The Chesapeake Bay Area Single Molecule Biology Meeting · Johns Hopkins University · Poster Haotian Wu (Author & Presenter), Spencer Jaquet (Author), Songon An (Author), Minjoung Kyoung (Author)
  • Modulating size distribution of glucosomes to understand their functional contributions to cellular redox homeostasis 2023 The Chesapeake Bay Area Single Molecule Biology Meeting · Johns Hopkins University · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Modulating size distribution of glucosomes to understand their size-dependent functional contributions to cellular redox homeostasis 2023 Graduate Research Day · UMBC · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Modulating size distribution of glucosomes to understand their functional contributions to cellular redox homeostasis 2023 The 2023 Annual Biochemistry and Molecular Biology Retreat · University of Maryland, School of Medicine · Poster Ashesh Sharma (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Functional Regulation of 4D Metabolic Network between Multienzyme Glucosome Condensates and Mitochondria 2022 The 2022 Annual Meeting of the American Society for Cell Biology (CELL BIO 2022 –ASCB/EMBO Meeting) · ASCB · Oral Presentation Minjoung Kyoung (Author & Presenter), Songon An (Author), Erin Kenndy (Author), Miji Jeon (Author)
  • Synchronizing glucosome size using optogenetics for its size-dependent functional characterization 2022 Chemistry/Biochemistry Graduate Research Day · UMBC · Poster Ashesh Sharma (Author & Presenter), Miji Jeon (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Size-Dependent Functional Oscillation of Glucosomes during the Cell Cycle Progression 2019 The Gordon Research Conference: Enzymes, Coenzymes and Metabolic Pathways · The Gordon Research Conference · Poster Miji Jeon (Author), Danielle L Schmitt (Author), Minjoung Kyoung (Author), Songon An (Author & Presenter)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2019 2019 ACS Middle Atlantic Regional Meeting · ACS · Poster Miji Jeon (Author & Presenter), Casey L Kohnhorst (Author), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2019 The Annual Frontiers at the Chemistry-Biology Interface Symposium · NIH · Poster Miji Jeon (Author & Presenter), Casey L Kohnhorst (Author), Minjoung Kyoung (Author), Songon An (Author)
  • Membraneless Metabolic Granules and Their Functional Contributions to Glucose Metabolism in Living Cells: the Glucosome 2019 Keystone Symposia - Biomolecular Condensates: Phase-Separated Organizers of Cellular Biochemistry (D5) · Keystone Symposia · Poster Miji Jeon (Author), Erin L Kennedy (Author), Minjoung Kyoung (Author), Songon An (Author & Presenter)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2019 Chemistry/Biochemistry Graduate Research Day · UMBC · Poster Miji Jeon (Author & Presenter), Casey L Kohnhorst (Author), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2019 The 2019 Biophysical Society Meeting (BPS2019) · Biophysical Society · Poster Miji Jeon (Author & Presenter), Casey L Kohnhorst (Author), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2018 The 3rd Chesapeake Bay Area Single Molecule Biology Meeting · Johns Hopkins University · Poster Miji Jeon (Author & Presenter), Casey L Kohnhorst (Author), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2018 The Annual Frontiers at the Chemistry-Biology Interface Symposium · UPenn · Poster Miji Jeon (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells. 2018 The 9th Annual Cancer Biology Research Retreat · University of Maryland School of Medicine · Poster Miji Jeon (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2018 The Annual Meeting of American Society for Biochemistry and Molecular Biology · ASBMB · Poster Miji Jeon (Author & Presenter), Casey L Kohnhorst (Author), Minjoung Kyoung (Author), Songon An (Author)
  • The Glucosome: A Metabolic Compartment for Glucose Metabolism in Living Cells 2018 Strategic Workshop on Imaging Subcellular to Cellular Cancer Biology · NCI and ASCB-Cosponsored · Poster Songon An (Author & Presenter), Minjoung Kyoung (Author)
  • Regulatory metabolic complex for glucose metabolism in living cells 2018 Annual Graduate Research Conference · UMBC Graduate School · Poster Miji Jeon (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • 4D spatial analysis of protein assemblies in metabolism with lattice light sheet microscopy 2018 Graduate Research Day · UMBC · Oral Presentation Erin Kennedy (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Regulatory metabolic complex for glucose metabolism in living cells 2018 Graduate Research Day · UMBC Chemistry and Biochemistry · Poster Miji Jeon (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Regulatory metabolic complex for glucose metabolism in living cells 2018 The Annual Biochemistry and Molecular Biology Retreat 2018 · University of Maryland School of Medicine · Poster Miji Jeon (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Regulatory metabolic complex for glucose metabolism in living cells 2017 2017 ACS National Meeting · ACS · Poster Miji Jeon (Author & Presenter), Minjoung Kyoung (Author), Songon An (Author)
  • Developing transient tertiary complexes with various binding affinities 2016 Summer Undergraduate Research Fest · UMBC · Poster Anthony Huynh (Presenter), Erin Kennedy (Author), Minjoung Kyoung (Leader)
  • Visualizing regulatory interactions in metabolic networks 2016 Gordon Research Conference · Gordon Research Conference · Poster
  • Developing Nanoscale Reactors for Single Molecule Studies 2016 Frontiers in Chemistry and Biology Interface Symposium · JHU · Poster Noah Robinson (Presenter), Minjoung Kyoung (Leader)
  • Cloning, Mutating and Labeling of FK506-binding Protein (FKBP) 2016 Undergraduate Research and Creative Achievement Day · UMBC · Poster Chidera Ekeocha (Presenter), Minjoung Kyoung
  • Engineering of the FRB domain of the mechanistic target of rapamycin (mTOR) 2016 Undergraduate Research and Creative Achievement Day · UMBC · Poster Sarah Pollock (Presenter), Minjoung Kyoung (Leader)
  • Developing Nano-reactors for Single Molecule Studies Utilizing Vesicle Fusion by Two Independent Methods 2016 Graduate Research Conference · UMBC · Poster Noah Robinson (Presenter), Minjoung Kyoung (Leader)
  • An approach towards efficient cancer immunotheraphy 2015 Summer Undergraduate Research Fest · UMBC · Poster Sarah Pollock (Author & Presenter), Danielle Schmitt (Author), Songon An (Author), Minjoung Kyoung (Leader)
  • Developing Nano Scale Vesicle-Reactor for Single Molecule Studies 2015 Graduate Research Conference · UMBC · Poster Noah Robinson (Author & Presenter), Minjoung Kyoung (Leader)

Courses Taught

  • Tutorial Projects Chem CHEM 393 · Spring 2017
  • Analytical Chemistry CHEM 300 · Spring 2017
  • Analytical Chemistry CHEM 300 · Spring 2017
UMBC UMBC
University of Maryland, Baltimore County
1000 Hilltop Circle, Baltimore, MD 21250 Directions & Parking

Resources

Important Contacts

Emergency Info

Contact Us

Apply

Top Stories of the Week

© UMBC: A University System of Maryland Member Institution