Dr. Ten-Tsao Wong

Associate Professor · Tenured

Department of Marine Biotechnology

College of Natural and Mathematical Sciences

About

Born in Taiwan, trained in Biology, Molecular Biology and Fish Reproductive Endocrinology, I enjoy hand-on research work and would like to develop my career as a research scientist.

Research interests

Fish Reproductive Endocrinology, Marine Biotechnology, Vaccine Development

Teaching interests

Molecular Biology, Fish Reproductive Endocrinology, Marine Biotechnology.

Education

  • Ph D, MEES — U of Maryland (2003)
    The Gonadal Endocrine Network Regulating Sex Reversal in The Gilthead Seabream
  • MS, Biochemistry/Molecular Biology — National Yang-Ming College of Medicine (1993)
  • BS, Biology — National Cheng-Kung University (1991)

Publications

  • The GNIH (Lpxrfa) system’s regulation of reproduction in the brain-pituitary axis of the zebrafish (Danio rerio). 2017 Biology of Reproduction · 96 (5) · pp. 1031-1042 Olivia Smith-Spicer, Nilli Zmora, Ten-Tsao Wong, Matan Golan, Berta Levavi-Sivan, Yoav Gothilf, Yonathan Zohar
  • Gonadotropin-releasing hormone 2 (Gnrh2) is necessary for reproductive success and oocyte maturation in fasted zebrafish (Danio rerio) Endocrinology Miranda Marvel, Ten-Tsao Wong, Nilli Zmora, Yonathan Zohar
  • Reproductive technology: sex control and sterilization in fish. Encyclopedia of Reproduction, 2nd edition · Elsevier · Accepted Ten-Tsao Wong, Yonathan Zohar

Presentations

  • Possible roles for GnRH3 in regulating pituitaryorganization in female zebrafish as revealed by neuronal ablation and snRNA sequencing 2023 12th International Symposium on Fish Reproductive Physiology · Keynote/Plenary Address Yonathan Zohar (Author & Presenter), Miranda Marvel (Author), Olivia Spicer (Author), Ten-Tsao Wong (Author), Nilli Zmora (Author)
  • Developing Technologies to Induce Reproductive Sterility in Eastern Oysters without Chromosome Set Manipulation. 2021 2021 National Shellfisheries Association 113th Annual Meeting · 2021 National Shellfisheries Association · Oral Presentation Lan Xu (Author & Presenter), Yonathan Zohar (Author), Ten-Tsao Wong (Author)
  • Developing Technologies to Induce Reproductive Sterility in Eastern Oysters without Chromosome Set Manipulation 2019 Aoshan Forum on Progress in Biotechnology for Marine and Fisheries · Ocean University of China · Oral Presentation Lan Xu (Author & Presenter), Kuan-Chieh Peng (Author), Yonathan Zohar (Author), Ten-Tsao Wong (Author)
  • Developing Technologies to Induce Reproductive Sterility in Eastern Oysters without Chromosome Set Manipulation Shizuoka city, Shizuoka, Japan. 2019 12th IMBC · International Marine Biotechnology Association · Oral Presentation Lan Xu (Author & Presenter), Kuan-Chieh Peng (Author), Yonathan Zohar (Author), Ten-Tsao Wong (Author)
  • Sterilizing fish by gene knockdown techniques. 2019 12th IMBC · International Marine Biotechnology Association · Poster Kuan-Chieh Peng (Author & Presenter), Yonathan Zohar (Author), Ten-Tsao Wong (Author)

Grants and Contracts

  • Developing new oyster sterilization technology to avoid triploid summer mortality 2019 NOAA Sea Grant · Grant · Funded Ten-Tsao Wong (Principal), Yonathan Zohar (Co-Principal)
  • Production of reproductively sterile Atlantic salmon to maximize cost-effective and environmentally-responsible U.S. aquaculture 2018 NOAA National Sea Grant · Grant · Funded Ten-Tsao Wong (Principal), Yonathan Zohar (Co-Principal)
  • Developing a fish sterilization technology to maximize cost-effective aquaculture production and minimize ecological impact. 2016 USDA-NIFA · Grant · Not Funded Yonathan Zohar (Co-Principal), Ten-Tsao Wong (Principal)

Research in Progress

  • Developing new oyster sterilization technology to avoid triploid summer mortality 2019 Scholarly · On-Going Ten-Tsao Wong, Yonathan Zohar, Louis Plough, Donald Webster
  • The role of germ cells in developmental organization and regulation of the reproductive endocrine network in zebrafish 2016 Scholarly · Planning

Patents and Intellectual Property

  • Methods of Agent Delivery into Eggs and Embryos of Egg-producing Aquatic Animals for Drug Screening, Agent Toxicity Assay and Production of Infertile Fish 2020 Patent · No. PCT/US2016/32873 · Licensed to Center for Aquaculture Technologies (CAT) Ten-Tsao Wong, Yonathan Zohar
  • Production of infertile fish through the administration of antisense morpholino oligomer against deadend mRNA to disrupt germ cell development 2014 Patent · No. 61968458 Yonathan Zohar, Ten-Tsao Wong
  • Production of infertile fish through the disruption of early gonadal development 2014 Patent · No. 61968458 Yonathan Zohar, Ten-Tsao Wong
  • Methods of producing infertile fish. 2013 Patent · No. 61904652 Yonathan Zohar, Ten-Tsao Wong

Courses Taught

  • Marine and Environmental Biotechnology MBIO 478/678 · Spring 2021
  • Marine and Environmental Biotechnology ENCE MEES · Spring 2017